Experimental cancer treatments for advanced stages are more effective than previously thought. Some oncology practitioners believe that experimental drugs are harmful - they give false hope to patients because of its low efficiency (long anticipated effectiveness of the experimental treatment with special drugs produced in Canadian pharmacy only at the level of 4-6% of cases). Patients in the final stage of the disease should have greater access to information about the experimental treatment programs, and, accordingly, they and their families should have the right to know what their real chances, with a particular treatment strategy. Scientists believe that the involvement of cancer patients even in the early stages of clinical trials can be very useful for them. Besides, the search for a way out of the situation means continuing the fight against the disease. It is characterized by academic phrase "treatment of metastatic cancer still remains palliative, with a very low probability of complete remission and cure the disease."

Peptide identification of Merkel Cell Carcinoma

Dear All,

as foreseen in the IMMOMEC project plan, our partners at immatics biotechnologies in Tübingen are currently intensively working on the identification of potential tumor-specific peptide targets for incorporation in the clinical immunomonitoring of the planned phase I trial. This work is a very important part of the IMMOMEC preclinical preparations, and the identified epitopes will hopefully enable us to observe and follow potential changes in tumor-specific immune responses of patients during study treatment.

However, in order to identify relevant target structures on tumor cells, the scientists at immatics heavily depend on the availability of MCC tissue (shock frozen in liquid nitrogen without additives; stored at -70C or lower after initial freezing). As this kind of material is very scarce, we are today contacting you with hopes that you may be able to support these efforts by providing such tumor samples for the mentioned analyses. Therefore, if such samples should be or become available at your hospital, the team at immatics would very much welcome the opportunity to discuss further details with you directly. For this, please do not hesitate to contact Dr. Nina Pawlowski (pawlowski@immatics.com) or myself (juergen.becker@medunigraz.at) at any time.

Thank you for your consideration and kind regards, Jürgen